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Call for Research / Review Articles


International Journal of Advance Microbiology and Health Research (IJAMHR)

I hereby want to invite you to submit a paper for the International Journal of Advance Microbiology and Health Research (IJAMHR).

We are pleased to inform you that we are started a new journal on health sciences and we are in the process of releasing our First Issue of First Volume of our journal. We would be grateful if you would submit a paper for to complete the first issue of first volume. Research Article, Review Article, Case Reports, and Brief Communication etc are welcome for possible publication in this issue.

It would be grateful if you could submit your paper on or before 15 September, 2017. If you are ready with the manuscript please submit your article at editorijamhr@gmail.com

Looking forward to hear from you soon
Thanks & Regards
Editor In-Chief
International Journal of Microbiology and Health Research


Developed By : Hashtag Solutions

Riya Kadam, Siddhesh Karanjekar, Kamanksha Mhatre, Vinayak Kamble, Yojana Kadam, Divya Kotian, Gurjeet Singh, A.D. Urhekar.

Study of Bacterial Pathogens and their Antimicrobial Susceptibility Pattern in Sputum Samples in Patients attending a Tertiary Care Hospital in Navi Mumbai
Int.J.Adv.Microbiol.Health.Res.2019; 3(3):10-15

Publisher: IJAMHR, Category: Current Issues



Abstract

Background: The morbidity and mortality still remain significantly high in patients with severe lower respiratory tract infections (LRTIs). In human beings these includes infection below vocal cords and it includes infections of trachea, bronchi and alveoli. We aimed to identify the causative bacterial agent, antibiotic sensitivity and resistance of hospitalized patients due to LRTIs in Navi Mumbai. Materials and Methods: A total of 150 sputum samples were collected in a wide mouth sterile container. All the samples were processed through Gram’s stain and culture. Bacteria were identified by standard protocols and antibiotic susceptibility was performed by Kirby Bauer disc diffusion method. Results: Out of 120 samples 65% were males and 35% were females. The median age group of males and females was 40 (10-60) years. 20% samples showed growth of normal flora, the 80% samples were considered as pathogenic organisms. Single and multiple pathogens were isolated from 88.54% and 11.46% respectively. The common single pathogen was Pseudomonas aeruginosa, Streptococcus pneumoniae, Klebsiella pneumoniae and Staphylococcus aureus. Streptococcus pneumoniae was sensitive to ampicilline/sulbactam and linezolid, gentamicin, cefotaxime and ciprofloxacin. Staphylococcus aureus was sensitive to ampicilline/sulbactam, linezolid, gentamicin and ciprofloxacin. Streptococcus pyogenes was sensitive to ampicilline/sulbactam, linezolid gentamicin and cefotaxime. Pseudomonas aeruginosa was sensitive to amikacin, lomifloxacin, netilline, gentamicin and cefoperazone. Klebsiella pneumoniae was sensitive to amikacin, netilline, lomifloxacin, gentamicin and cefoperazone. Acinetobacter baumanii was sensitive to netilline. Escherichia coli was sensitive to amikacin, gentamicin. Conclusion: The predominant organisms isolated from LRTIs were Pseudomonas aeruginosa, Streptococcus pneumonie, Klebsiella pneumoniae. ampicillin+sulbactam, linezolid, gentamicin, cefotaxime, amikacin and ciprofloxacin demonstrate high level of sensitivity on respiratory tract pathogens. This study supports use of ampicillin+sulbactam, linezolid, gentamicin, cefotaxime, amikacin and ciprofloxacin as appropriate in the patients with LRTIs.


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