Chetan Sushil Javsen, Y.A. Deshmukh

To Study Effect of Topical Betamethasone Dipropionate on Blood Pressure, Blood Sugar and Blood Calcium in Healthy Volunteers
Int.J.Adv.Microbiol.Health.Res.2020; 4(1):1-9

Publisher: IJAMHR, Category: Current Issues

Abstract

Corticosteroids are mainly used to reduce inflammation and suppress the immune system. Corticosteroids are used in a variety of conditions, ranging from brain tumours to skin diseases. In the skin diseases, corticosteroids are used for few days to few weeks and use of different corticosteroids according to potency, depends on site (location) of application and severity of disease. Adverse effects of corticosteroids depend on potency of corticosteroids, duration of treatment and area of involvement. In this study we investigated the effect of topical high potent betamethasone dipropionate on blood pressure, blood sugar and blood calcium after four hours in healthy volunteers. Also, correlated the absorbed concentration of corticosteroids with blood pressure, blood sugar, blood calcium and affected body surface area. Four hours after betamethasone application there was no effect on blood pressure, blood sugar and blood calcium level in healthy volunteers.