Prevalence of HCV Genotypes in Various Geographical Regions
Publisher: IJAMHR, Category: Current Issues
Hepatitis C Virus (HCV) belongs to the Flaviviridae family. It’s a positive -sense single- stranded RNA virus. The RNA contains about 3000 amino acids. It was first found in the year 1989. HCV is an important emerging viral infection affecting most parts of the world. HCVhas several genotypic variationsand is crucial for clinical, epidemiological studies and treatment. Genotypes play a vital role in SVR. It contains 7 genotypes (1-7) and various subtypes. The types are identified by gene order of the HCV RNA 5’-C-E1-E2-p7-NS2-NS3-NS4A-NS4B-NS5A-NS5B-3.This paper summarizes the prevalence of genotypes in various geographical regions and the methods to identify different genotypes.
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