Call for Research / Review Articles

International Journal of Advance Microbiology and Health Research (IJAMHR)

I hereby want to invite you to submit a paper for the International Journal of Advance Microbiology and Health Research (IJAMHR).

We are pleased to inform you that we are started a new journal on health sciences and we are in the process of releasing our First Issue of First Volume of our journal. We would be grateful if you would submit a paper for to complete the first issue of first volume. Research Article, Review Article, Case Reports, and Brief Communication etc are welcome for possible publication in this issue.

It would be grateful if you could submit your paper on or before 15 September, 2017. If you are ready with the manuscript please submit your article at editorijamhr@gmail.com

Looking forward to hear from you soon
Thanks & Regards
Editor In-Chief
International Journal of Microbiology and Health Research

Developed By : Hashtag Solutions

Charu Thakur and Bhairav Prasad

Antiinflammatory Activity of Stem Bark of Rhamnus purpureus
Int.J.Adv.Microbiol.Health.Res.2019; 3(1):21-28

Publisher: IJAMHR, Category: Current Issues


This study was facilitated to screen the anti-inflammatory effect of bark of the Rhamnuspurpureus.Rhamnuspurpureus frequently known as Gaunta . it is deciduous shrub originatedin the Himalayan range, Himachal Pradesh and Bhutan. In present study the stem bark of Rhamnuspurpureus was chopped and extracted in ethanol butenol, chloroform and evaluated for carregenum, cotton pallet induced granulloma in Wister Albino Rats. The results revealed that cruedethonolic extract showed maximum inhibition in caragenum induced rat paw edema followed by ethanol, butenol, and chloroform extract. The ethonolic extract of infective dose 200mg/kg body weight exhibit remarkable anti inflammatory activity with inhibition of 41.05%, 49.35%, 54.30%, and 54.77%, and butanolic extract showed significant results viz. 46.01%, 49.80%, 49.17%, 50.28%. and the standard drugs indomethacin also compared (10mg/ kg) showed inhibition of 50.69%, 51.63%, 50.46%, 51.78% after 1,2,3,and 4 hours of treatment respectively. The result indicates that the ethonolic extract as well as butonilic extract revealed strong inflammatory activity while chloroform showed less effective in comparision with indomethicin. The order of inhibition of carregenum induced rat paw edema was establish to be - indomethecine> ethanol >butonol>chloroform>. In conclusion to above study it has been seen that the Rhamnuspurpureus was found to have great anti-inflammatory response and can be substitute or alternative for synthetic or chemically derived drugs.


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